Monday, January 27, 2020

Why Lawrence Krausse Is Wrong On The "Doomsday Clock" - Why It Needs To Keep Ticking





The Bulletin of the Atomic Scientists website recently warned ('Why The World Is Closer Than Ever To Doomsday'')


"On Thursday, the Bulletin of the Atomic Scientists, which takes stock of the threats posed by nuclear war and climate change each year, moved the Doomsday Clock to 100 seconds before midnight. We are now measuring how close the world is to catastrophe in seconds -- not hours, or even minutes. It is the closest to Doomsday we have ever been since the clock was created in 1947.
The Bulletin of the Atomic Scientists, which was founded by those who worked on the Manhattan Project during World War II, and now includes 13 Nobel Laureates on the board, issued a statement on Thursday that read, "Humanity continues to face two simultaneous existential dangers—nuclear war and climate change—that are compounded by a threat multiplier, cyber-enabled information warfare, that undercuts society's ability to respond. The international security situation is dire, not just because these threats exist, but because world leaders have allowed the international political infrastructure for managing them to erode." 
But physicist Lawrence Krausse isn't buying it (WSJ, 'Time To Stop The Doomsday Clock', Jan. 23), p. A15, writing:
"The Bulletin of the Atomic Scientists is resetting its “Doomsday Clock,” which has stood still since 2018 at two minutes to midnight. I was a member of the Bulletin’s Board of Sponsors for a dozen years and chaired it from 2009 through 2018, and I think it’s time to retire the clock."

He then quotes founding editor Eugene Rabinowitch, who explains the clock's purpose:

“The Bulletin’s Clock is not a gauge to register the ups and downs of the international power struggle. It is intended to reflect basic changes in the level of continuous danger in which mankind lives in the nuclear age.”

Let's also note that no serious scientist treats it as an exact quantitative measure of danger. It is more  an analog -based estimate of probability embodied in an image anyone can grasp.  (Much like the descending ball in NYC on New Year's Eve is purported to be a chronological countdown to the New Year.)   The Doomsday Clock then embodies a potential countdown for humanity's end (as opposed to the end of an expired year) - factoring in the differing probabilities for the cumulative threats facing us.  

A more precise interpretation might be as an analog estimate of the multiple correlation of mounting dangers to the time we have left to address them,  before they lead to our extinction.   One can even conceive of the clock as a kind of pictorial - image based multiple regression scenario of the cumulative threats at a given time, t. In this latter one is aware of not one but multiple (regressor) variables in relation to the predicted danger of "doom",  D.  These regressors  constitute  a set of threat variables, ranging from a Torino 9 asteroid  strike ('x1'), to all - out nuclear war ('x2'), to runaway greenhouse effect, 'x3', to uncontained bird flu pandemic 'x4', etc.

Krauss continues:
"Early on, it often did. It moved forward in 1953, after the U.S. and the Soviet Union developed the hydrogen bomb, or in 1974, when missiles with multiple warheads became a reality. But gradually it broadened focus beyond the physical dangers of nuclear weapons and began taking account of political questions such as arms-control treaties and tensions between India and Pakistan, and, since 2007, of other military threats such as bioterrorism, as well as the global existential dangers of climate change. The 2019 announcement also cited “fake news” and Donald Trump."

Here, Krausse seems to want to sideline these political threats but they are very real.  For example, the nuclear threat  involving India and Pakistan could easily expand to a larger nuclear war.  Bioterrorism also is not to be underplayed, given we would not like to see the release of a weaponized smallpox or Ebola virus - or the bubonic plague. 

 As for Trump, common sense would alert the sentient citizen to the intolerable risk of a narcissist egomaniac who has control of nearly 6000 nuclear warheads- but no control of himself, or self-awareness in respect of his limitations.  In a real manner of speaking, so long as Trump is around we are all living with a ticking human time bomb - and no one knows when it will go off, or what will set it off.

Krausse again:
"This multiplication of threats has heightened the sense of alarm. The Doomsday Clock time is now much closer to midnight than it was during the Cuban Missile Crisis (seven minutes), when the world really was on the precipice of a nuclear holocaust. At the same time, a clock that has moved back and forth while lingering frighteningly close to midnight for more than 70 years strikes many as crying wolf. At two minutes to midnight, the clock can’t move much further forward, even if threats increase."

Here I beg to differ with Lawrence that the Cuban Missile Crisis (which I lived through while living in Miami, FL in October, 1962) is equal to the nuclear threat that exists now.  The reason?  At the time the U.S. and USSR combined had a total of roughly 200 nuclear warheads- and long range ICBMs (e.g. Atlas missiles) to deliver them.  Cuba had an estimated 93 intermediate range missiles (IRBMs compliments of the Russians) which it was prepared to use IF the U.S. had tried to invade or attack. (Fortunately we had JFK at the helm and not the likes of the bellicose buffoon Trump.)  Had war been unleashed it would have been bad for sure - with up to 100 million dead or dying -but not anything near the 5 billion that would perish today  because of 10,000 nuclear warheads (in an all out nuclear war) and a likely "nuclear winter" to follow.

The back and forth movement of the clock to which Krausse refers is not "crying wolf" but simply acknowledging that the probability of  incipient threats can vary over a long time- and even year to year.   The proximity to midnight merely indicates  the variability of this threat potency and also  that we haven't done a damned thing to address the most catastrophic, namely proliferation of nuclear weapons, and the approaching runaway greenhouse effect.  Worse,  we now face the specter of hypersonic ICBMs which leave virtually no early warning time before nuclear strikes- radically amplifying nuclear threats.

Add in the latter, say the Russians - then the U.S. - developing thousands of them, and the clock can indeed move much closer to midnight - say 30 seconds or even closer. What else would you expect from thousands of such hypersonic weapons each with a megaton or larger warhead that could strike any U.S. city within minutes?  
"More to the point, the threats the clock now purports to measure are different in kind. Nuclear weapons could end human civilization in a day. The generation of greenhouse gases associated with human industrial activity won’t. It is increasingly likely to have devastating impacts, but these will emerge over the long term and be spread unevenly across the globe."
Krausse is right in a way, but not totally.  It is true nuclear weapons in general would have a more catastrophic (and immediate)  effect than climate change - but not necessarily.  It is conceivable an all out nuclear war - say carried out in hours - could take many lives but still leave 2-3 billion alive, for a time. However, if nuclear winter sets in those lives too would be snuffed out in 10-20 years.  Analogously, if climate change isn't controlled it may lead to the runaway greenhouse effect by the end of the century (say with a  6C increase in global mean surface temperatures) that could end the existence of most humanity within 10-20 years. 
"Psychologist Steven Pinker argues—and the bulletin admits—that the clock is anything but a scientific instrument. In Mr. Pinker’s view, the annual announcement is a publicity stunt that demeans the scientific community and makes the world seem more dangerous than it actually is."

I have already dispelled Pinker's Pollyannish views in a previous blog post, e.g.
And shown the world is indeed as dangerous and replete with threats as it appears to the sentient and aware citizen. 

Back to Krausse:
"The clock is a publicity stunt—and a successful one. That was the point. The public hardly ever debates the ever-present danger of a world with 10,000 nuclear weapons. People would rather not think about it."
Yet there’s a deeper problem. Not only is the Doomsday Clock unscientific; the factors of its setting are now dominated more by policy questions than scientific ones. The former may be important, but claiming the authority of “atomic scientists” is appropriate only for the latter."

I totally disagree with Larry's take the clock is a "publicity stunt",  because there is no stunt aspect to it, as I described in my opening paragraphs.  If anyone wishes to behold a publicity stunt look no further than Trump's lawyers' performance at his Senate impeachment trial. There you will see a blizzard of lies, disinformation, distractions and propaganda the likes of which would do Goebbels proud. A publicity stunt for the ages and in the service of treason.

Krausse would do better to move away from his 'cartoon' view and see the clock instead  as a compact pictograph synthesizing  a multiple regression outcome for incipient threats at any one time. These threats are real - albeit variable in potency and imminence- hence the (visual) device which incorporates them is no "stunt". Further, it is based on rational interpretation and decision-making (including on policies that affect scientific quality, outcomes)  so shares with science - atomic,  astrophysics or other - the critical attribute of reason.

 Further, policy decisions can and do impact scientific ones - often adversely.  For example, Krausse cannot deny that the Trump cabal's policies, e.g.  on climate change,  have actually worsened the climate situation globally.   The dilution of many regulations including allowing more CO2 and methane to be discharged into the atmosphere, not to mention easing of water pollution standards for rivers, streams,  are not in anyway helpful to averting the worst climate scenarios - including the runaway greenhouse effect.

Add in the Trumpists' savage attack on the ACA ("Obamacare") which could conceivably leave up to 30 million without any health care and you have the makings of a human catastrophe set to become vastly larger in the event of the next flu pandemic.  See e.g.
Krausse again:

"But today the clock’s setting is determined more by concerns about how superpowers can engage in arms-control talks, about potentially reckless statements by world leaders, or about what policies would best reduce carbon emissions. These are important questions, but not ones on which scientists can claim special authority."

OK, admittedly they are not questions on which scientists can claim an exclusive  ("special") authority - but they are certainly ones on which they can claim a pre-eminent authority. Hence, would in general carry much more insight than a politician's - say in terms of how carbon emissions beyond a certain threshold would lead to the runaway greenhouse effect. Or how the future failure of arms control talks - say to do with hypersonic ICBMs- may pave the way for much greater likelihood of a nuclear holocaust

"The group announcing the clock reset includes a former president of Ireland, a former United Nations secretary-general and members of the Elders, an organization founded by Nelson Mandela that describes itself as “independent global leaders working together for peace and human rights.” These like-minded people—along with various intelligence and climate policy experts, and one atomic scientist—can make informed recommendations, and I largely agree with them. But this is public policy, not science."

Again, Krausse confuses the clock with an actual scientific  paper, argument or measuring device -  which it is not. It is a quasi scientific, public policy tool that adopts an easy to grasp visual representation  ("clock") to estimate the variable probability of humanity's proximity (in time) to ultimate perdition.  
"So why not retire the clock? An icon with some fixed value, say, five minutes to midnight, might serve as a permanent reminder of a dangerous world. Nuclear weapons aren’t disappearing any time soon, and climate change is already occurring on a massive scale. Other threats will emerge, even as technology creates opportunities for revolutionary improvements in the human condition."
The clock cannot be retired precisely because leaving it at a fixed position (say 5 minutes to midnight) would erroneously convey the message of a fixed probability for  future collective threats. Thus, a 5 minutes to midnight full stop would lull most citizens of the planet into thinking all further movement toward midnight had ceased. So all is well and let's party! 

This then would also ensure the world more likely falls into a complacent attitude and makes no attempt to curb nuclear proliferation or significantly reduce carbon emissions hurling us toward the runaway greenhouse.  It is exactly the wrong thing to do and I am amazed a guy that actually was part of the process at one time would advocate this.

No, nuclear weapons aren't "disappearing" anytime soon, but that doesn't mean inroads can't be made, say in halting or removing the threat of hypsersonic delivery systems.  And while climate change is indeed already occurring on a massive scale there is still time to avoid the calamity of the runaway greenhouse - if we act now to do so.  But fixing the clock at one position is an invitation to do nothing because well, 'Hey look! It ain't moving any closer to the witching hour so why worry?'

"The Bulletin of Atomic Scientists can continue to play a useful role by focusing on providing accurate information on technology and science to be used as a basis for public policy. Or it could rename itself The Bulletin, acknowledge that it is an advocacy organization, and make the best case for its well-intentioned proposals."

This is a non-starter. "The Bulletin"?   Seriously? People who thrive on 'clickbait'  and spend most days buried in their smart phone screens for the latest buzz would simply yawn and move on.  The power of the doomsday clock is precisely because the IMAGE of motion toward midnight catches attention.  And attention in these hurly- burly,  distracted times is hard to capture.  Hence, Krauss'e prescriptions here are basically equivalent to remaining silent (or out of sight) in spite of the  sundry variable threats and their changing probabilities.

Sorry, no can do, Lawrence.

Saturday, January 25, 2020

Poor Little Reep Senators "Bored" Having To Sit Still & Listen During Trial - Maybe It's Time These Useless Imps Get Real Jobs



"What a bunch of entitled complainers. Thousands of Americans do precisely this each day serving in jury duty, yet some of these elected officials -- elected precisely to serve their constituents and pay attention in one of the rarest Senate proceedings to take place -- cannot muster the self-discipline and stamina to actually sit still, pay attention, and reach an impartial determination. My 10 and 12 year old sons have better discipline, self-control, and manners than these clowns." - 'Chloe' - commenting about bored GOP Senators (NY Times)


We learned Friday (WSJ, 'Marathon Days Make Many Senators Antsy', p. A4)  that Senators (mostly Repukes),  required to sit through the Trump impeachment trial in silence and without their smart phones, have "grown increasingly comfortable testing those rules" as the trial wears on.

According to Senator Kevin Cramer, Republican of North Dakota.:

"We’re doing our best.  With each break and with each disruption if you will, to the sitting in the chair, there becomes a little less discipline."

Awww...boo hoo and hoo.  Cry me a river you worthless little imp. An historical Senate trial is under way requiring your rapt attention and you choose to make excuses to fritter away time.

Incredibly, despite impeachment trial rules that require them to sit silently at their desks when the proceeding is in session, senators have increasingly been wandering out for short or long breaks, to accommodate bathroom stops, telephone calls and even cable television appearances. On Thursday afternoon, as the Democratic impeachment managers took turns speaking during their second full day of presentations, at least 19 Reepo senators could briefly be seen out of their seats.
Some rose from their chairs and crossed the chamber to whisper to one another, while others exited the chamber entirely for 15- to 20-minute stretches and could be seen in the cloakrooms on their phones.
Those who remained in their seats often took up some elaborate distractions. Senator Rand Paul, Republican of Kentucky, who was noodling over a crossword puzzle on Wednesday, could be seen on Thursday laboring over a detailed sketch of the Capitol. Senator John Cornyn, Republican of Texas, twice appeared to swipe at an Apple watch on his wrist, despite the ban on electronics. Multiple senators, in an apparent attempt to rouse themselves, could be seen vigorously chomping on gum- including Tom Cotton and Joni Ernst.

Meanwhile, Ben Sasse brought in a tin of Red Man  chewing tobacco, right onto the Senate floor. (If you've ever dealt with this stuff - as I have had to  with AK students in space physics labs- and seen the spittle left behind you'd know it ain't cool.)  Well, at least he had to bury it when the sergeant-at -arms chastised him.

During the lunch break on Thursday, Senator Richard M. Burr, Republican of North Carolina, passed out fidget spinners for his 52 Republican colleagues, the better to pass the time.

Fidget spinners?   NO wonder so many refer to you morons as Reeptards.  Don't you bozos have the minimal focus to pay attention for the time - excepting lunch, dinner and restroom breaks?    The plague of inattention and ploys to avoid doing their duty reached such a point that Barry Black - the Senate chaplain- opened Thursday's session with the following prayer (WSJ, ibid.):

"Lord, help them to remember that listening is often more than hearing. It can be an empathetic attentiveness that builds bridges and unites."

The WSJ piece goes on to try to portray the difficulty of conducting an historic Senate trial in the modern world - beset as it is with millions of distractions, social media intrusions etc.:

"The wandering attention of some lawmakers reflects the challenge of holding antiquated trial proceedings in the smart phone era, when most Americans reflexively scroll and click through periods of tedium.

Unlike their counterparts in 1789, who set the parameters for impeachment in the Constitution, Senators today rarely sit and listen to complex oral presentations for hours on end.""

Well, maybe it's past time that changed.  Perhaps - if these cretins possess the attention span of slugs- they aren't truly qualified to be in the Senate. Maybe they ought to leave and form their own 'old boys' club somewhere - a place they can fidget spin, do crosswords, chew gum, chomp Red Man, and blow farts to their heart's content. Perhaps they simply aren't up to the cerebral stature of their forbears and the founders. 

Among the lamest of excuses is one offered by Sen. John Barrasso (WY) who opined (ibid.):

"If you really want to play close attention, you can't do it from your seat. You have to do from either standing in front of the video screens or in the cloakroom watching the CSPAN video."

Which is total horse pockey that wouldn't be tolerated by any judge worth his salt in any jury trial.  Imagine an ordinary juror in a criminal case whining to the judge that he can pay better attention outside watching a closed circuit TV screen than seated in the jury box.  The judge would issue a contempt warning on the spot, as Justice Roberts ought to have done once this imbecile's BS was made public.  But it shows the degree to which Roberts has allowed flouting of the rules to escape sanction.

The irony is that the whole process might have been truncated had the Reep Senators simply allowed witnesses as the Dems proposed, and also just voted Trump to be removed from office as the leprous, vile orange ape he is.

Of course, then Trump's base of losers would have ensured their senate reps be primaried. But at least then they'd no longer have to suffer the evident scourge of "boredom" in listening to complex oral presentations.

Here are some of the choice comments from NY Times readers about these losers:

"SENATORS: DO YOUR JOBS! Wake up or get a new job. You are now jurors in a sordid bribery case involving the most openly corrupt POTUS ever. " "The American people are watching. The world and our allies are watching. History is watching. This is not a game."

"Pathetic. Remember when you thought Senators were professional serious people who knew what their job was knew how to do their job and actually did serious work for the American public? It was fun to be a kid."

"For every minute a senator is not engrossed in listening, we should dock their salaries. Shameful. The fate of our nation, indeed our planet, lies in the hands of these people who have blinders on and refuse to face facts. I hope details of attendance and attentiveness is reported back to their constituents and each one vote they may cast should be reduced by fractions based on undivided attention."

"Undisciplined rule-breakers and cheaters. It's how they run their lives; it's how they "do their jobs." Throw the bums out. Make them get real jobs, where their employer is actually watching them, and holding them to account."

I personally am all in with the last two comments especially, in respect of: 1) docking their salaries for every minute they're not at their desks listening, and 2) engineering and pushing for the loss of  their seats to qualified  Dems - to at least make them look for real jobs. Since they clearly don't treat the Senate as such.

Friday, January 24, 2020

Federal Aviation Advisory Panel's Report On Boeing's 737 MAX Is More Cover Up And Nonsense

Image may contain: one or more people and suit
Boeing's new CEO (David Calhoun) is convinced the public will be 'all in' and get back on the MAX when pilots do, and regulators approve it.

It is often said while watching certain movies, mainly science fiction (e.g. 'The Matrix'), that you have to strongly apply the suspension of disbelief. Else, within minutes you are likely to cease conscious viewing and simply erupt into peals of unconstrained laughter at the nonsense coming at you. Well, I had pretty well that identical reaction on reading the recent account (WSJ, 'Panel Backs How FAA Gave Safety Approval For 737 MAX', January 17, p. A4).   This was after reading the following codswallop:

"A federal advisory panel evaluating the safety approval process for Boeing's 737 MAX concluded regulators adhered to policies in certifying the plane and determined it wouldn't have been safer if it had received the scrutiny of an all new aircraft."

Of course, that is tommyrot and balderdash.  First, the approval process and certification - mainly letting Boeing itself have at it - was full of holes and misfires,  apart from which you have a 'fox guarding the henhouse' scenario.See e.g.:


https://www.seattletimes.com/business/boeing-aerospace/failed-certification-faa-missed-safety-issues-in-the-737-max-system-implicated-in-the-lion-air-crash/

In addition it is a bold-faced lie to claim the jet would not have been safer in the mode of an all new aircraft.  As I pointed out in my Nov. 14 post, "A proper redesign of Boeing's MAX 8  would require extending the fuselage height, and thereby not getting a simple recertification. "  

More mind-boggling in the case of the piece is when one reads (ibid.)

"Lee Moak, co-chairman of the independent committee set up last year declined to identify the mistakes made during certification of the now -grounded jets,  instead describing current procedures as 'appropriate and effective'."

Which is more horse pockey, especially given that within a day of that report's exposure in the WSJ we learned a new software problem had emerged.  This one involves the software preventing the jet's  flight control computers  from powering up and also verifying they are ready for flight- according to industry and government officials (WSJ, 'Boeing Finds Another Software Problem', January 18, p. A1)

The new issue was uncovered  (ibid.) when:  "engineers were loading the updated software - including an array of changes painstakingly developed over roughly a year- into the flight control computers of a test aircraft". 

Pardon me, but this shows me Moak is out to lunch, and the whole "let Boeing certify the thing" was nutso  - plus unsafe (including the whole MCAS system as well). Also, contrary to Moak's twaddle  all the "current procedures" are nowhere near adequate or safe if this software- developed over a year- wasn't even found  defective until being loaded into an actual aircraft.   Let's also note this revised software was "intended to fix the automated MCAS system" - to prevent the plane from crashing again.

Again, another reminder why I never want to see the inside of this flying boondoggle.  Even for a short trip to Vegas.

As if this new software glitch wasn't enough, barely a week earlier Boeing was forced to admit (finally) that Ipad training wasn't sufficient and flight simulators were needed for training. (Following which we learned Boeing had insufficient simulators to proceed with pilot training when - and IF - the MAX is ever re-certified. ) 

The latest  'MAX' fiasco intruded a day ago when Boeing announced it doesn't expect federal regulators to approve its changes to the grounded plane until this summer.  Which means, of course, it won't be flying this summer - but more likely months later- if ever.  Even if approved this summer all 'MAX' -using airlines - e.g. Southwest, United, American - will need additional time to train their pilots on flight simulators.  Already, Boeing has had to set aside $9 billion to cover customer compensation - for loss of parts of their fleets- as well as  working through the backlog of orders (4,500 jets).

Personally, as I wrote before, this monstrosity ought not be airborne, period, because of its severe design flaws.  As I noted, no software "fix" should be used to correct what is in essence an aerodynamic design flaw.

Moak's clownish "federal advisory panel" report received the best brush off from Rep. Peter DeFazio of Oregon, Chairman of the House Transportation Committee who said (WSJ earlier item):

"It would be the height of irresponsibility to leave the (certification) delegation system as is and just hope for the best."

Indeed, and this move - daft as it is - certainly wouldn't impress or coax the flying public into getting inside one of these glorified tin can "self -hijacking"  contraptions anytime soon. In the most recent surveys, more than 50 percent of flyers would choose another aircraft - or not fly at all.

Never mind. Boeing's new CEO -David Calhoun-   is totally convinced the flying public will be there lining up to get on the MAX once regulatory approval passes. ("And pilots get on that airplane and support that airplane" (WSJ,  'Boeing CEO Puts Faith In MAX', today, p. B1, Business & Finance).

Well, maybe. Until the next crash - then all bets are off. 


Thursday, January 23, 2020

How Valid Are The Oft-Cited Stats For Cancer "Survival" Rates?

nice map image.jpg
Prostate image yielded as part of 3D staging biopsy with cancerous lesions in mud yellow, urethra in green. This is completed prior to focal cryotherapy treatment  - where a cryo-probe at -90C is inserted into the perineum to freeze cancer cells.  The procedure can last from an hour to an hour and forty five minutes. But no promises are made to rid the cancer entirely.


The recent press reports of lowered cancer survival rates, and a WSJ editorial on the subject, make it incumbent on critical- thinking citizens to examine such stats and whether they're really valid.  We read in the WSJ piece from January 9, for example, that: "the cancer death rate in the U.S.  fell 2.2. % from 2016 to 2017 "the largest single year drop ever recorded".   This according to the latest report in the American Cancer Society.   However, we also learn:

"The drop is largely driven by progress against lung cancer".

A result of great new terrific treatments? Actually not. More a case  that such lung cancer deaths were largely fueled by "fewer people smoking."

Meanwhile  we learn that (ibid.):

"Doctors made progress in breast, prostate and colorectal cancers."

But how much?  According to a WSJ editorial ('Where You Want To Get Cancer', January 10, p. A16):

"The five year survival rate is now 98 % for prostate cancer, 92% for melanoma and 90 % for breast cancer"

But what does that even mean and is it 'more pie in the sky'  or wishful thinking than anything else?   A recent issue of Skeptic magazine (vol. 24, No. 4, 2019) provides some clues in an article entitled 'How Much Longer Will Cancer Screening Myths Survive?'  The author, Felipe Noguiera, cites two problems with figuring survival rates associated with screenings:

1)The lead time bias. I.e. when statistical studies include already screened patients, and

2) A length of time bias which occurs when screening is done periodically and cancer- contrary to what most people think - is a heterogeneous disease with different progression rates.

A key problem in respect of (1) which I've discussed before in the case of prostate cancer (when I referred to radiation, and radical prostatectomy treatments) is that screening allows many cancers to now be detected in the asymptomatic phase.  That was how my prostate cancer was detected using a needle biopsy back in July, 2012 e.g.

Notes on a Prostate Biopsy: Don’t Fear and Don’t H...

In my case I was told non-action (e.g. watchful waiting) was not an option so I had to choose either the surgery (RP) or radiation. Well, I ended up choosing high dose brachytherapy in September that year.  But four years later the cancer (evidently diagnosed from MRI biopsy, fusion biopsy and 3D screening- staging biopsy results e.g.

3D Staging Prostate Biopsy Unlikely To Come Into...

Returned. Would I have still survived this long (e.g. nearly 6 1/2  years) without any treatments?  (I had another, focal cryotherapy treatment in June, 2017) The jury is still out according to the Skeptic author. As he writes (p. 34):

"Imagine that a group of patients without screening is diagnosed due to symptoms at an age of 63 years, but they die from the cancer at 65. Now, consider that screening (e.g. biopsy) detects the tumor at age 59 and the patients still die at 65.  Thus, without screening the 5 year survival rate was 0 % but with screening it is 100 %, even though screening did not make them live any longer. Both groups of patients died at the same time.  This is called the lead time bias."

In terms of (2), the effect arises because screening is done periodically( in my case, in July, 2012, in June 2016, September, 2016 and January, 2017.   As the author points out:

"Basically, aggressive and more lethal cancers tend not to be detected by screening because they grow fast and cause symptoms between screening rounds. Similarly, screening tends to detect slow, progressive cancers.  As a result a group of patients whose cancers were detected by screening will live longer than those diagnosed clinically imply because screening selected a group of patients with a better prognosis."

In other words, the success wasn't on account of the screening per se, but because that screening selected for the slower growing cancer.   As the author adds:

"That means that screening detects abnormalities that meet the pathological criteria of cancer, but would not have caused symptoms or death in the patient's lifetime. This is called overdiagnosis."

The problem of overdiagnosis is that at the time of diagnosis it is not possible to know which cases will progress and which will not. So almost everyone is treated leading to overtreatment. That leads to another complication, i.e. "to look only for cancer specific mortality could miss deaths caused by treatment."

He then cites (p. 36) Swedish trials of mammography to show the problem of bias associated with cancer-specific mortality in breast cancer. Thus:

"For every other woman screened every other year for 12 years - while one cancer death was avoided, the total number of deaths increased by six."

In other words, the increased radiation endured in mammography screenings led to other cancers not related to the one originally detected and which caused a death.   The conclusion?

We should publicly acknowledge that we cannot be sure whether early detection lengthens, shortens or has no effect on how long people live."


This comports with what I wrote in my November 9, 2018  blog post on the changed recommendations for prostate cancer screening, for example, e.g.


"Most experts agree that people with a life expectancy of 10 years or less don't need routine screening for cancer. One problem is that overscreening can lead to overdiagnosis and overtreatment. For instance, a screening might find a slow-growing cancer that wouldn't cause any harm within a person's lifetime if left undetected, a situation that's common with prostate cancer. If that's the case, it's not worth the burden and anxiety caused by testing and the potential for more—possibly invasive—follow-up procedures.

Yet, according to published studies, too many older adults continue to undergo unnecessary cancer screenings despite age- and health-related recommendations from professional groups.

Three groups that have weighed in on prostate cancer screening are the National Comprehensive Cancer Network (NCCN), the United States Preventive Services Task Force (USPSTF), and the American Urological Association (AUA). Following are their current recommendations for when to stop:

I'd also posted this on the Team Inspire prostate cancer forum and was met with a lot of pushback, some downright vitriolic, i.e.

"What are you a politician running for office? An insurance company agent? I am sick of you guys coming in here and trying to tell us to try to control costs and not to get these tests! I don't care how much they cost, even if I'm 78 I am gonna get them! Maybe I want to live to 95!"

 "I'm in no position to contradict medical science on this, but 70 seems a bit young. Yes, it leaves a "life expectancy" of 10 years (in 2018, living in the U.S., given today's technology), but healthy people with good genes and healthy  lifestyles routinely live well into their 90s. My G4+5 was discovered when I was 59. What if it had been 12 years later? Answer: a horrible death from PCa, diagnosed only after I became symptomatic, and far too late to treat it."

So there's no doubt that because of the feel good propaganda pushed by the likes of the WSJ editors (and other corporate media)  it will be a long time before people back off on the benefits of screening, and indeed adhere to the revised recommendations.

Adam Schiff Delivers Performance Of A Lifetime - But It Mostly Fell On Closed Minds, Deaf Ears



Even as we learned Trump yesterday tweeted 142 times (141 of them outright lies)  we  got to see and hear the stirring words of Adam Schiff ringing loudly and clear in the Senate Chamber:

“You are left with no choice but to demand to hear from each witness with firsthand knowledge” of Trump’s pressure campaign, A fair trial requires nothing less.”

The historic trial, only the third of its kind in U.S.  risks devolving into a farcical Potemkin sham unless the 53 Republicans pull their collective heads out of their asses and attend to the case and the arguments presented by those like Schiff.   They ought to be reminded they are also on trial  - along with Trump - as history suffuses the chamber including the presence in the room of John Roberts, the chief justice of the U.S. Supreme court.

Just after 1pm, Adam Schiff stepped to a lectern between the tables to narrate the sordid story of Trump’s wrongdoing. Schiff and the other 6  House impeachment  managers laid out their case in stages, to powerful effect.  (At least for anyone of normal sentience - as opposed to the Repuke kool aid drinkers and Dotard asslickers like Lindsey Graham).  In meticulous detail they presented Trump’s corrupt scheme in narrative form, with a factual chronology and video of past witness testimony, to move thereafter to a description of the constitutional framework for impeachment.

But Schiff's presentation blew everyone away with its powerful combination of appeal to the Constitution, Senators' moral conscience and the future welfare of the nation.  At a break in the trial, the minority leader, Chuck Schumer, called Schiff’s performance “a tour de force”.  He said:

“I think a good number of my Republican colleagues for the first time heard the argument against the president – powerfully, succinctly and completely– and I hope that can begin to change minds,” 

Both wifey and I concurred that Mr. Schiff delivered an argument for the ages, in clear, concise terms given he had to bring all the evidence to bear on Trump's extortion of the Ukrainian president and his subsequent obstruction. Hell, the orange, pus-filled maggot even bragged while still in Davos of his crime, keeping the materials hidden, e.g.


Polling released on Wednesday by the Pew Research Center indicated public backing for the Democratic call for witnesses and found that 70% of respondents said Trump “definitely or probably acted unethically” while 51% said Trump “should be removed from office”.

“We’re trying this case over two juries,” Schiff said. “The Senate and the American people.”

But have any Republican Senators been moved to action?  Hardly!

“I didn’t hear anything new today,” said Republican Pat Toomey of Pennsylvania.

 Errr... were you really conscious then, Toomey, or on an MJ candy high?

“I haven’t heard any evidence in there that the president’s done anything wrong,” said Josh Hawley of Missouri. 

Then you need to take remedial American Government classes again, Hawley, with emphasis on Article 1 of the Constitution.

Lisa Murkowski, (R-Alaska) then reportedly chafed at Jerry Nadler's remark that any Senator who refuses to allow witnesses is effectively assisting Trump in the "cover up".  Miffed at any such suggestion, Murkowski whined: "I am very offended!  I took it as very offensive since I am listening attentively and working hard to ensure a fair process."

Spare me the faux offense, Senator. If you are not prepared to allow witnesses - especially relevant ones to this supposed trial - then all you're doing is posturing for FOX News zombies.   And that also means, logically, you are assisting in Trump's obstruction!  Which also means collaborating in the cover up. (See news link above how he bragged about withholding materials.)

Meanwhile, Lindsey Graham yelped about a "crusade" by the Dems to get his master, Dotard.  After seeing this dishonorable puke  cry, bark and barf,  one had to wonder if he was missing his latest Trump ass lick fix.  Or maybe he's on some kind of brain -frying junk, given he also congratulated Schiff on a "job well done".  Which is it, Lindsey?

With the majority leader, Mitch McConnell, having succeeded the night before in winning approval for a speedy trial, the House prosecutors have limited time in which to plant seeds of doubt in Republican minds about the conduct of the president.  But for realists, the odds of getting any such seeds planted are about the same as Tau Ceti aliens abducting Dotard before he leaves bellows another lie.

There is also the issue here of Mitch McConnell's "rules" which appear to have any force at all.  One often beheld the Senate Repukes visibly frustrated at the long hours of the trial, appearing at times to be on the verge of mild mutiny, openly flouting rules requiring them to remain at their desks and instead circulating in a cloakroom off the Senate floor. They drew no rebuke from Roberts.  My take? Roberts correctly saw the truth was gradually infiltrating their neurons risking about one trillion neural embolisms - so gave the Reeptards a break.

The seven House managers selected to present the articles of impeachment have about 16 remaining hours spread over two days to present their case to convict and remove Trump from office. Then the Dotard team has its opportunity to rebut the charges.   Translation:   Jay Sekulow and Co. will strain to see how many lies and concocted bullshit they can come up with (mainly using Russian tropes) to  appease their master, Dotard - and to hell with the Constitution and country.

Trump of course is not expected to appear at his own trial.  He bragged in Davos he'd like to come, but of course those are the empty words of a con man.  You take everything this twit says or tweets with less than a National Enquirer headline.

 Moderate Republican senators (e.g. Susan Collins, Murkowski, Cory Gardner, and Mitt Romney )  have made cooperative noises and also expressed discomfort with rushing the proceedings.  But this is likely all political posturing - especially for those up for re-election -  like the weasels Gardner and Collins.  Point:  none of the "moderates" voted with Democrats on several motions on Tuesday that would have cleared the way for new witnesses and testimony.  Clearly, Trump has their brains and spines locked up firmly in the remote recesses of his fat behind - never to see the clear light of day.

Winding up his oratory, Schiff warned that democracy was on the line. “Our future is not assured. A fair trial, with impartial consideration of all of the evidence against the president, is how we keep our republic.”

As Ben Franklin once told a woman who asked what kind of government we had: "A Republic, if you can keep it."    Right now it appears that owing to the cowardice of the Republicans, and their placing party over nation, we may not keep it - but lose it to an authoritarian Trumpocracy.

See also:



And:
And